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Join date: Mar 14, 2025
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Aug 6, 2026 ∙ 3 min
PD-1-Enhanced HIV Therapeutic Vaccine ICVAX® Completes Phase I Clinical Trial, Moving Closer to Real-World Application
In a major translational achievement for Hong Kong’s biomedical innovation sector, the Centre for Virology, Vaccinology and Therapeutics (CVVT) is pleased to highlight significant progress in the development of ICVAX®, a novel therapeutic DNA vaccine aiming to achieve a functional cure for HIV. Led by Prof. Zhiwei Chen, Deputy Director of CVVT, Director of the AIDS Institute at the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), and Chair Professor of Immunology and...
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Jul 20, 2026 ∙ 4 min
CVVT Deputy Director Zhiwei Chen and HKUMed–Tsinghua Team Develop First-In-Class Broad-Spectrum Small-Molecule Antiviral to Combat Sars-Cov-2 and Related Coronaviruses
The ongoing evolution of SARS-CoV-2, particularly the rapid emergence of the Omicron variant and its sub-lineages, has weakened the effectiveness of existing vaccines and antiviral drugs, underscoring the potential risk of future coronavirus pandemics. In response, a joint research team featuring leadership from the Centre for Virology, Vaccinology and Therapeutics (CVVT) with their team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) as well as the School of...
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Jul 20, 2026 ∙ 4 min
Breakthrough in Influenza Defense: Organoid-based Studies Reveal Cross-Protective NA Antibodies Against H5N1 Viruses
A groundbreaking study led by BiomOrgan Limited, a spin-off company from the Centre for Virology, Vaccinology and Therapeutics (CVVT), has leveraged its proprietary respiratory organoids to provide a novel platform for developing influenza vaccines and antibodies. They revealed a critical human immune mechanism that provides natural cross-protection against emerging H5N1 influenza viruses, including the cattle-associated clade 2.3.4.4b strain. The study was spearheaded by Prof. Zhou Jie...
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