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Targeting papain-like protease for broad-spectrum coronavirus inhibition. Protein Cell.

Dec 2022

Yuan S*, Gao X, Tang K, Cai JP, Hu M, Luo P, Wen L, Ye ZW, Luo C, Tsang JO, Chan CC, Huang Y, Cao J, Liang R, Qin Z, Qin B, Yin F, Chu H, Jin DY, Sun R, Chan JF, Cui S*, Yuen KY*

Production of single-cycle infectious SARS-CoV-2 through a trans-complemented replicon. J Med Virol.

8 Aug 2022

Cheung PH, Ye ZW, Lui WY, Ong CP, Chan P, Lee TT, Tang TT, Yuen TL, Fung SY, Cheng Y, Chan CP, Chan CP, Jin* DY.

Peptidic defective interfering gene nanoparticles against Omicron and Delta SARS-CoV-2 variants and influenza A virus in vivo. Signal Transduction and Targeted Therapy

 3 Aug 2022

Hanjun Zhao*, Chuyuan Zhang, Hoiyan Lam, Zheng Peng, Xinjie Meng, Lu Lu, Man Lung Yeung, Kin-Hang Kok, Jasper Fuk-Woo Chan, Kelvin K. W. To, Kwok-Yung Yuen*

SARS-CoV-2 IgG seropositivity after the severe Omicron wave of COVID-19 in Hong Kong. Emerg Microbes Infect.

5 Sep 2022

Poon RW, Chan BP, Chan WM, Fong CH, Zhang X, Lu L, Chen LL, Lam JY, Cheng VC, Wong SSY, Kok KH, Yuen KY, To KK.

Human nasal organoids model SARS-CoV-2 upper respiratory infection and recapitulate the differential infectivity of emerging variants. mBio

8 Aug 2022

Chiu MC, Li C, Liu X, Song W, Wan Z, Yu Y, Huang J, Chu H, Cai J, Kai-Wang To K, Yuen KY, Zhou J#.

Coronaviruses exploit a host cysteine-aspartic protease for replication. Nature.

3 Aug 2022

Chu H, Hou Y, Yang D, Wen L, Shuai H, Yoon C, Shi J, Chai Y, Yuen TT, Hu B, Li C, Zhao X, Wang Y, Huang X, Lee KS, Luo C, Cai JP, Poon VK, Chan CC, Zhang AJ, Yuan S, Sit KY, Foo DC, Au WK, Wong KK, Zhou J, Kok KH, Jin DY, Chan JF, Yuen KY.

Aberrant splicing events caused by insertion of genes of interest into expression vectors. Int J Biol Sci.

18 Jul 2022

Cheng* Y, Kang XZ, Chan P, Ye ZW, Chan CP, Jin* DY.

A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2. Science Bull (Beijing).

15 Jul 2022

Chen J, Wang P, Yuan L, Zhang L, Zhang L, Zhao H, Chen C, Wang X, Han J, Chen Y, Jia J, Lu Z, Hong J, Lu Z, Wang Q, Chen R, Qi R, Ma J, Zhou M, Yu H, Zhuang C, Liu X, Han Q, Wang G, Su Y, Yuan Q, Cheng T, Wu T, Ye X, Zhang T, Li C, Zhang J, Zhu H, Chen Y, Chen H, Xia N.

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1. Laboratory: Unit 208-213, 2/F,  Building 15W, Hong Kong Science Park, Pak Shek Kok, N.T.

2. Office: Unit 313-316, 3/F, 
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