RESEARCH FOCUS
VACCINES
Key Projects:
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Development of DelNS1 live attenuated vaccine system for influenza and respiratory viral diseases, and as an immune enhancer for cancer antigens
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Improvement of injectable vaccines by intradermal vaccination with topical adjuvant
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Improvement of injectable vaccines by intramuscular vaccination with novel systemic adjuvant
Programme Leaders:
Professor Honglin CHEN
Dr Kelvin Kai-Wang TO
Key Research Staff:
Professor Dongyan JIN
Dr Anna Jinxia ZHANG
Professor Ning-Shao XIA
Professor Xiao-Ning XU
BI-SPECIFIC NEUTRALIXING ANTIBODY PLATFORM FOR VIRAL PATHOGENS
Key Projects:
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Engineer bnAbs and bi-bnAbs with improved breadth and potency for protection against multisubtype HIV-1 strains or against respiratory viruses
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Synergistic effect of bnAb and bi-bnAb against a large panel of genetically divergent pseudotype viruses and primary isolates in vitro and in vivo
Programme Leader:
Professor Zhiwei CHEN
Key Research Staff:
Professor David D. HO
Professor Lingqi ZHANG
Professor Dongqing ZHOU
Professor Honglin CHEN
Antivirals Targeting Host Factors
Key Projects:
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Development of broad-spectrum antiviral agents targeting the virus-induced metabolic reprogramming
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Targeting the cell fate pathways as novel antiviral strategies
Programme Leader:
Dr Kin-Hang KOK
Key Research Staff:
Dr Jasper Fuk-Woo CHAN
Dr Shuofeng YUAN
Dr Hin CHU
Professor Stanley PERLMAN
Antivirals Targeting Viral Factors
Key Projects:
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Antiviral agents targeting structural proteins of viruses
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Development of broad spectrum antivirals by evaluating defective interfering genes and antiviral peptides
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Rational design and synthesis of a defective interfering virus for anti-influenza therapy / Flu A DI viruses and coronaviruses
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Establishing human and animal organoids for virus studies
Programme Leader:
Dr Jasper Fuk-Woo CHAN
Key Research Staff:
Dr Richard Yi-Tsun KAO
Dr Kin-Hang KOK
Dr Hanjun ZHAO
Dr Jane Jie ZHOU
Dr Philip Man-Lung YEUNG
Professor Shibo JIANG
Professor Lu LU
Professor Hans Clevers
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CONTACT US
E-mail: admin@cvvt.hk
Tel: 3910 3688
Fax: 3753 2284
Address:
1. Laboratory: Unit 208-213, 2/F, Building 15W, Hong Kong Science Park, Pak Shek Kok, N.T.
2. Office: Unit 313-316, 3/F,
Building 17W, Hong Kong Science Park, Pak Shek Kok, N.T.