RESEARCH FOCUS

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VACCINES

Key Projects:

  1. Development of DelNS1 live attenuated vaccine system for influenza and respiratory viral diseases, and as an immune enhancer for cancer antigens

  2. Improvement of injectable vaccines by intradermal vaccination with topical adjuvant

  3. Improvement of injectable vaccines by intramuscular vaccination with novel systemic adjuvant

Programme Leaders:

Professor Honglin CHEN

Dr Kelvin Kai-Wang TO
 

Key Research Staff:

Professor Dongyan JIN

Dr Anna Jinxia ZHANG

Professor Ning-Shao XIA

Professor Xiao-Ning XU

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BI-SPECIFIC NEUTRALIXING ANTIBODY PLATFORM FOR VIRAL PATHOGENS

Key Projects:

  1. Engineer bnAbs and bi-bnAbs with improved breadth and potency for protection against multisubtype HIV-1 strains or against respiratory viruses

  2. Synergistic effect of bnAb and bi-bnAb against a large panel of genetically divergent pseudotype viruses and primary isolates in vitro and in vivo

Programme Leader:

Professor Zhiwei CHEN

Key Research Staff:

Professor David D. HO

Professor Lingqi ZHANG

Professor Dongqing ZHOU

Professor Honglin CHEN

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Antivirals Targeting Host Factors

Key Projects:

  1. Development of broad-spectrum antiviral agents targeting the virus-induced metabolic reprogramming

  2. Targeting the cell fate pathways as novel antiviral strategies

Programme Leader:

Dr Kin-Hang KOK

 

Key Research Staff:

Dr Jasper Fuk-Woo CHAN

Dr Shuofeng YUAN

Dr Hin CHU

Professor Stanley PERLMAN

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Antivirals Targeting Viral Factors

Key Projects:

  1. Antiviral agents targeting structural proteins of viruses

  2. Development of broad spectrum antivirals by evaluating defective interfering genes and antiviral peptides

  3. Rational design and synthesis of a defective interfering virus for anti-influenza therapy / Flu A DI viruses and coronaviruses

  4. Establishing human and animal organoids for virus studies

Programme Leader:

Dr Jasper Fuk-Woo CHAN

 

Key Research Staff:

Dr Richard Yi-Tsun KAO

Dr Kin-Hang KOK

Dr Hanjun ZHAO

Dr Jane Jie ZHOU

Dr Philip Man-Lung YEUNG

Professor Shibo JIANG

Professor Lu LU

Professor Hans Clevers

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CONTACT US

E-mail: admin@cvvt.hk

Tel: 3910 3688

Fax: 3753 2284

Address:

1. Laboratory: Unit 208-213, 2/F,  Building 15W, Hong Kong Science Park, Pak Shek Kok, N.T.

2. Office: Unit 313-316, 3/F, 
Building 17W, Hong Kong Science Park, Pak Shek Kok, N.T. 

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